One of the hardest raid dungeons in the game currently, The temple of Ahn'Quiraj is home to a ghastly assortment of bugs and strange creatures. Placed in the desert of Silithus, The Temple of Ahn'Quiraj is the 40-man side of the entire Ahn'Quiraj complex.

Before even attempting this dungeon you must have been able to master places such as Molten Core, Blackwing Lair, and the 20-man version, The Ruins of Ahn'Quiraj. Also, to progress very far you will need an extremely high nature resistance, come prepared

From the World of Warcraft Site:

At the heart of Ahn'Qiraj lies an ancient temple complex. Built in the time before recorded history, it is both a monument to unspeakable gods and a massive breeding ground for the qiraji army. Since the War of the Shifting Sands ended a thousand years ago, the Twin Emperors of the qiraji empire have been trapped inside their temple, barely contained behind the magical barrier erected by the bronze dragon Anachronos and the night elves. Now that the Scepter of the Shifting Sands has been reassembled and the seal has been broken, the way into the inner sanctum of Ahn'Qiraj is open..

Skeram
Yauj, Lord Kri, Vem
Sartura
Fankriss
Viscidus
Huhuran
Twin Emperors
Ouro
C'Thun